Hydrogel-Coated Near Infrared Absorbing Nanoshells as Light-Responsive Drug Delivery Vehicles
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چکیده
منابع مشابه
Hydrogel-Coated Near Infrared Absorbing Nanoshells as Light-Responsive Drug Delivery Vehicles
Nanoparticle drug delivery carriers that can modulate drug release based on an exogenous signal, such as light, are of great interest, especially for improving cancer therapy. A light-activated delivery vehicle was fabricated by synthesizing a thin, thermally responsive poly(N-isopropylacrylamide-co-acrylamide) hydrogel coating directly onto the surfaces of individual near-infrared (NIR) absorb...
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This paper describes the preparation and characterization of a new type of composite nanoparticle, where the structure consists of a nontoxic hydrogel polymer network that encapsulates a gold shell/silica core. These composite nanoparticles are being developed as photothermally responsive drug-delivery vehicles that undergo structural changes slightly above physiological temperature. A unique p...
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This report describes the development of optically responsive gold nanoparticles ( 60 nm in diameter) coated with a thermally responsive biocompatible hydrogel overlayer (20–90 nm thick). The hydrogel consists of a mixture of N-isoproprylacrylamide and acrylic acid; this copolymer can be tailored to exhibit a lower critical solution temperature (LCST) slightly above physiological temperature. W...
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Introduction Hydrogels have been extensively investigated as drug delivery carriers in biomedical applications.The stimuli-responsive hydrogel is generally created when an ionic monomer is incorporated into the hydrogel network, in which the charged group is formed and called fixed charge since its mobility is much less than that of freely mobile ions within the interstitial fluid. In this stud...
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ژورنال
عنوان ژورنال: ACS Biomaterials Science & Engineering
سال: 2015
ISSN: 2373-9878,2373-9878
DOI: 10.1021/acsbiomaterials.5b00111